Axford was one of the best closers in all of baseball in 2011, posting 46 saves as the Brewers made the National League Championship Series.
2012 has been a different story, however. Axford has a 2-6 record with a 5.35 ERA. He has converted only 16 of 22 save opportunites. The right-hander had blown only 5 saves combined in 2010 and 2011.
Francisco Rodriguez will take over for Axford as Milwaukee's closer. Rodriguez has 292 career major league saves, but has served as a set-up man for the Brewers since being acquired in a trade from the Mets in July of last year.
Milwaukee hosts St. Louis tonight at Miller Park in game 2 of a three-game series.