Rodgers connected with Greg Jennings and Donald Driver for scores and was also intercepted twice on 19-of-31 throws. Jennings led all receivers with 82 yards on five receptions, while Driver hauled in his 50th career touchdown amid a five-catch, 30-yard day.

Ryan Grant limped off in the first half with an ankle injury and did not return. Brandon Jackson filled in admirably and ran for 63 yards on 18 carries as Green Bay (1-0) won its fourth straight season opener.

It was the Packers' first win in Philadelphia since 1962, having lost eight consecutive trips to the City of Brotherly Love.

Kevin Kolb's long-awaited tenure as the Eagles' starting quarterback was met with disaster. The fourth-year pro was making his third career start and first since the team shipped long-time signal-caller Donovan McNabb to the Redskins in the offseason.

Kolb was flat in completing 5-of-10 passes for 24 yards before being knocked out of the game with a concussion. He was chased down from behind by the Packers' Clay Matthews on a third-down scramble and landed hard on the ground under the weight of the tackle. His head and left knee were driven into the turf simultaneously as he fumbled the ball out of bounds.

Kolb came back out for the next series before being replaced by Michael Vick to start the second half. Vick was crisp in hitting on 16-of-24 throws for 175 yards and a touchdown in leading Philadelphia back from a 17-point deficit in the fourth. He ran for another 103 yards on 11 attempts but the Eagles (0-1) fell just short in the end.

Matthews put forth a dogged effort on defense for Green Bay, totaling seven tackles, two sacks and a forced fumble. He stopped Vick on 4th-and-1 at the Green Bay 42 on the first play after the two-minute warning to essentially seal the victory.