Albert Pujols was 4-4 at the plate, crushing 2 home runs and driving in five against Brewers starting pitcher Yovani Gallardo. Rafael Furcal and Matt Holliday also homered for St. Louis.
The Brewers drop to 81-57 on the season, but maintain a 7.5 game lead over the Cardinals in the National League Central Division. The two teams meet once again in St. Louis next week.
Milwaukee begins a three game weekend series against the Houston Astros on Friday night in Texas.