The two suspects arrested are juveniles and one has a relationship of some kind with the victim, but police are not saying what type.
The 78-year-old woman was found lying in her garage with a large amount of blood around her.
Police responded to the home after receiving a call from a family member.
Twelve hours after arriving at the crime scene, police arrested the two juvenile suspects and placed them in the Sheboygan County Detention Center.
They both face first degree intentional homicide.
According to police the woman was targeted and died of blunt trauma.
Police say there is no need for the community to be alarmed about their safety because the victim was targeted.
Her name is not being released pending family notification.